Valium and Xanax are both brand names of different generic drugs, which have different effects, prescriptions and side effects. Valium may be absorbed slightly comparing to Xanax, but the difference is still minimal. Peak concentrations of both medications usually occur during 1-2 hours after inhibition. Effects of Xanax last 4 – 6 hours on average, while effects of Valium last approximately 4 hours. Both, Valium and Xanax, like all benzodiazepines, act to enhance the actions of a neurotransmitter in the brain, which is called GABA (Gamma-Aminobutyric Acid). A research was conducted to directly compare Valium and Xanax for the anxiety disorder treatment. Based on results, Valium is slightly more beneficial comparing to Xanax at relieving anxiety, particularly in cases where the anxiety was also accompanied by depression. However, the differences were not really significant to be meaningful clinically. Xanax generally comes in a smaller dosage (i.e. 0.25, 0.5, 1 or 2mg) comparing to Valium (2, 5, 10mg).
Generally, benzodiazepines with a shorter half-life (i.e. Xanax) are harder to stop comparing to those with a longer half-life (i.e. Valium). Both medications readily enter brain tissue, which reinforces drug taking and is basically associated with withdrawal symptoms, which more severe.